Efficacy and safety of pharmacological treatments for Patent Ductus Arteriosus closure: a systematic review and network meta-analysis of clinical trials and observational studies. Marconi E, Bettiol A, Ambrosio G, Perduca V, Vannacci A, Troiani S, Dani C, Mugelli A, Lucenteforte E. Pharmacol Res. 2019 Aug 31:104418. doi: 10.1016/j.phrs.2019.104418. [Epub ahead of print] Review.PMID:Â 31479749 Efficacy and safety profiles of different pharmacological interventions…
Pharmacological interventions for the prevention of fetal growth restriction: protocol for a systematic review and network meta-analysis. Bettiol A, Lombardi N, Crescioli G, Avagliano L, Mugelli A, Ravaldi C, Vannacci A. BMJ Open. 2019 Jul 26;9(7):e029467. doi: 10.1136/bmjopen-2019-029467. Fetal growth restriction (FGR) includes different conditions in which a fetus fails to reach the own full growth, and accounts for 28%-45% of…
Pattern of Use and Long-Term Safety of Tyrosine Kinase Inhibitors: A Decade of Real-World Management of Chronic Myeloid Leukemia Alessandra Bettiol,Ettore Marconi, Niccolò Lombardi, Giada Crescioli, Filippo Gherlinzoni, Thomas Walley, Alfredo Vannacci, Alessandro Chinellato, Pietro Giusti Background and Objectives First-line treatment of chronic phase (CP) chronic myeloid leukemia (CML) is based on the first-generation tyrosine kinase inhibitor (TKI) imatinib…
BACKGROUND: Inter-patient variability in response to opioids is well known but a comprehensive definition of its pathophysiological mechanism is still lacking and, more importantly, no studies have focused on children. The STOP Pain project aimed to evaluate the risk factors that contribute to clinical response and adverse drug reactions to opioids by means of a systematic review and a clinical…